I. General Concepts

Scope of Pediatric Environmental Medicine
History of Pediatric Environmental Medicine
Environmental Disasters in History
Definition
Epidemiology & Surveillance
Cluster Investigation
Taking An Environmental History
Medical Assessment
Laboratory Analysis
Environmental Testing
Biomarkers of Exposure
Analytical Methods
Patient Management
Antidotes
Research Methods & Design
Biostatistics
Reading the Scientific Literature Critically

International Issues in Pediatric Environmental Health
Climate Change
Equity & Social Disparities
Ethical Issues in Environmental Health
Legal Issues & Public Policy
Global Solutions
International Agencies and Resources

Pregnancy & Lactation
Developmental Toxicology
Reproductive Environmental Health & Toxicology
Placental Transmission of Toxins
Fetotoxicity, Teratogenicity
Embryogenesis
Breast Milk Contaminants

Childhood Environments
Household Hazards
Traffic & Pedestrian Hazards
Playgrounds
Water Pollution
Sewage & Hygiene
Hazardous Waste Sites
Toxic Waste Dumps
Hospital Wastes
Military Munitions & Anti-Personnel Devices
Brownfields
Scavenging & Waste Dumps
Child & Adolescent Labor, Occupational Toxic Exposures & Injuries
Marksmanship & Lead Poisoning
Noise Pollution
Agricultural Injuries
Arts & Crafts
High Risk Industries
Smelters
Agriculture
Mining & Quarries
Refineries
Nuclear Reactors
Electrical Generating Facilities
Military Munitions & Antipersonnel Hazards
Sick Building (& Sick School) Syndrome

Complex Childhood Environmental Diseases
Allergies & Atopy
Asthma
Birth Defects
Childhood Cancer
Developmental Disorders
Autism, Pervasive developmental disorders
Neurobehavioral Conditions
Selected endocrine disorders
Multiple Chemical Sensitivities
Obesity

Environmental Hazard Reduction
Risk Assessment for Toxic Hazards
Risk Management
Risk Communication
Material Safety Data Sheets & Threshold Levels
Poisoning Prevention
Injury Prevention
The Built Environment
Environmental Litigation & Regulatory Remedies
Community Planning & Resources
Advocacy

Environmental Health Resources
EPA website
TRI database
IARC
OTIS
IRIS database
ATSDR Toxfiles

II. Environmental Toxicology

Heavy Metals
Lead
Mercury
Organics: Methylmercury, Dimethylmercury
Inorganic Mercury & Mercuric Salts
Metallic Mercury
Arsenic
Arsenite
Arsenate
Organic Arsenic Compounds
Arsine Gas
Manganese
Cadmium
Copper
Thallium
Metallic Compounds
Organometals
Metal Oxides
Other Metals
Nickel
Chromium
Beryllium
Zinc
Aluminum
Magnesium
Radium
Uranium

Persistent Organic Compounds
PCBs, PBBs, Furans, Dioxin
Chlorinated dibenzo-p-dioxins
Perfluoro-alkyl Substances (PFAS or Perfluoro Chemicals “PFCs”)
Hexachlorocyclohexane
Hexachlorocyclopentadiene
Endocrine Disruptors

Airborne Gases & Toxins
Smoke & Fumes
Ozone
Oxides of Nitrogen & Sulfur
Formaldehyde & Other Aldehydes
Halogen Gases & Ammonia
Phosgene
Acrolein
Hydrogen Sulfide

Indoor Airborne Gases & Toxins
Carbon Dioxide
Carbon Monoxide
Environmental Tobacco Smoke
Dust Mites, Cockroach Antigen, Other Allergens
Indoor Molds & Fungi
Particulates
Asbestos
Formaldehyde

Flame Retardants
TRIS
Phosphate esters
Polybrominated diphenyl ethers (PBDE)

Ionizing & Non-ionizing Radiation
Uranium, Plutonium, & Radio-isotopes
Radon
Lasers
Non-ionizing Electromagnetic Radiation
Ultraviolet Light

Pesticides, Herbicides, & Fumigants
Organochlorine Pesticides
Chlordane
Dieldrin
Organophosphate Insecticides
Methyl parathion
Carbamate Insecticides
DEET
Pentachlorophenol
Pyrethrins
Herbicides
Ethylene Oxide
Fungicides
Biocides
Fumigants
Phosphine
Methyl Bromide

Caustic Compounds
Inorganic Acids & Bases
Organic Acids & Bases
Hydrofluoric Acid

Solvents & Organic Chemicals
n-Hexane
Phenol
Methylene Chloride
Phthalates
Carbon Disulfide
Volatile Organic Compounds (VOCs)
Trichloroethylene, tetrachloroethylene, dichloroethylene
Polycyclic Aromatic Hydrocarbons
Benzo-a-pyrene (BaP)
Benzene
Toluene, Xylene, Xylol
Gasoline, Other Petroleum Distillates, Hydrocarbons
Ethylene Glycol, Higher Glycols
Toxic Alcohols: Methanol, Ethanol

Biological Agents
Mycotoxins
Fungi
Plants
Legionella
Snakes, Spiders, Stinging or Biting Animals
Foodborne Illness
Herbs, Ethnic Remedies & Dietary Supplements
Natural Fibers, Byssinosis, Baganossis
Manmade Fibers

Chemical & Biological Warfare Agents
Nerve Gases
Tabun (GA)
Sarin (GB)
Soman (GD)
GF
VX
Vesicants
Mustard
Lewisite
Lacrimators
CN
CS
Capsacin
Other Gases
Phosgene, Diphosgene
DM (Adamsite)
Biological Agents
Bacteria
Anthrax, Plague, Tularemia, Brucellosis
Rickettsiae
Q Fever
Viruses
Smallpox
Encephalitides, Hemorrhagic Fever
Toxins
Botulinum
Ricin
Pyrogenic Toxins
Trichothecene Mycotoxins

Inorganic Chemicals
Cyanide, Hydrogen Cyanide, Cyanide Salts
Nitriles, Azides
Nitrates, Nitrites
Diisocyanates, Methyl-isocyanate
Asbestos
Fluorine, fluorosis
Chlorine, Bromine
Sodium
Potassium
Phosphorus
Methemoglobin-Forming Chemicals

REFERENCE TEXTS

Achievements in Children’s Environmental Health
Amler R.W., Smith L. (editors)
ATSDR
Atlanta Georgia
2001

Handbook of Pediatric Environmental Health, 3rd Edition
Etzel R.A., Balk S.J. (editors)
American Academy of Pediatrics
Elk Grove Village, IL
2011

Pediatric Environmental Health
Landrigan P, Etzel R (editors)
2014

JOURNALS

Archives of Disease in Children & Adolescents
Clinical Toxicology
Environmental Health Perspectives
Journal of Pediatrics
Pediatrics

MONOGRAPHS

National Academy of Sciences:

WEBSITES
www.iseepi.org
www.pehsu.net
www.conferences.ubc.ca/iseaisee2002/
www.epa.gov.us
www.atsdr.gov.us
www.cdc.gov.us