Season 2 Episode 7: A Safer Slice: Can Wheat Be Engineered to Prevent Celiac Disease?

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Could science reshape wheat to make it safer and possibly prevent celiac disease? In this episode of Raising Celiac, we talk with Maria Rottersman, a doctoral researcher at UC Davis, about groundbreaking work to remove the most harmful gluten proteins from wheat using gene deletions. We explore how this innovation could reduce risk for millions, what it means for breadmaking, and what comes next. Plus, we follow Markus, a teen at genetic risk for celiac, whose story brings hope to families everywhere.

 

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Could science reshape wheat to make it safer and possibly prevent celiac disease? In this episode of Raising Celiac, we talk with Maria Rottersman, a doctoral researcher at UC Davis, about groundbreaking work to remove the most harmful gluten proteins from wheat using gene deletions. We explore how this innovation could reduce risk for millions, what it means for breadmaking, and what comes next. Plus, we follow Markus, a teen at genetic risk for celiac, whose story brings hope to families everywhere.

 

Learning Objectives:  At the conclusion of this educational program, learners will be able to:

  1. Describe the scientific approach used to remove immunogenic gluten proteins from wheat through targeted gene deletions.
  2. Discuss the potential implications of low-immunogenic wheat for preventing or reducing risk of celiac disease in genetically susceptible individuals.
  3. Evaluate the challenges and considerations related to baking quality, consumer acceptance, and future clinical research of modified wheat strains. 

In support of improving patient care, Boston Children’s Hospital is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

 

 

Physician

Boston Children’s Hospital designates this live activity for a maximum of 0.5 AMA PRA Category 1 Credits ™. Physicians should claim only credit commensurate with the extent of their participation in this activity.

Social Worker

As a Jointly Accredited Organization, Boston Children’s Hospital is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. State and provincial regulatory boards have the final authority to determine whether an individual course may be accepted for continuing education credit. Boston Children’s Hospital maintains responsibility for this course. Social workers completing this course receive 0.5 ACE CE continuing education credits.

Nurse

Boston Children’s Hospital designates this activity for 0.5 contact hours for nurses. Nurses should only claim credit commensurate with the extent of their participation in the activity. 

Dietician

Boston Children’s Hospital designates this activity for 0.5 contact hours for dieticians. Dieticians should only claim credit commensurate with the extent of their participation in the activity.

Disclosure Policy 

Boston Children’s Hospital adheres to all ACCME Essential Areas, Standards, and Policies. It is Boston Children’s policy that those who have influenced the content of a CE activity (e.g. planners, faculty, authors, reviewers and others) disclose all relevant financial relationships with commercial entities so that Boston Children’s may identify and resolve any conflicts of interest prior to the activity. These disclosures will be provided in the activity materials along with disclosure of any commercial support received for the activity. Additionally, faculty members have been instructed to disclose any limitations of data and unlabeled or investigational uses of products during their presentations.

Disclosure Statement

The following planners, speakers, and content reviewers, on behalf of themselves, have reported the following relevant financial relationships with any entity producing, marketing, reselling, or distributing health care goods or services consumed by, or used on patients: 

Vanessa Weisbrod: None

Janis Arnold, MSW, LICSW: None

Maria Rottersman: None

Additional information

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Faculty

Vanessa Weisbrod headshotVanessa Weisbrod
Director, Celiac Disease Program

 

 

 

 

Janis Arnold headshot

Janis Arnold, MSW, LICSW

Clinical Social Worker, Division of Gastroenterology, Hepatology, and Nutrition

 

 

 

Maria Rottersman headshotMaria Rottersman

A doctoral researcher at the University of California Davis