Description

In this course, neonatal neurologist Dr. Janet Soul reviews the evaluation and management of neonatal seizures, with a particular emphasis on distinguishing acute symptomatic seizures from neonatal-onset epilepsy. Dr. Soul highlights common etiologies such as hypoxic-ischemic injury, metabolic disturbances, and genetic epilepsies, and discusses how seizure timing, semiology, and EEG findings inform diagnosis. The session underscores the importance of careful clinical assessment and appropriate use of EEG in guiding treatment decisions. Designed for clinicians involved in neonatal care, this content supports improved diagnostic accuracy and evidence-based medical management of seizures in newborns. This presentation was recorded at the Lennox-Lombroso Pediatric Epilepsy Conference on September 19, 2025.

Learning Objectives: 

At the conclusion of this educational program, learners will be able to:

1. Describe the long-term sequelae of neonatal seizures
2. Interpret evidence regarding the efficacy and safety of antiseizure medications for neonatal seizures
3. Differentiate management of acute symptomatic seizures from neonatal-onset epilepsy

In support of improving patient care, Boston Children’s Hospital is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Disclosure Policy 
Boston Children’s Hospital adheres to all ACCME Essential Areas, Standards, and Policies. It is Boston Children’s policy that those who have influenced the content of a CE activity (e.g. planners, faculty, authors, reviewers and others) disclose all relevant financial relationships with commercial entities so that Boston Children’s may identify and resolve any conflicts of interest prior to the activity. These disclosures will be provided in the activity materials along with disclosure of any commercial support received for the activity. Additionally, faculty members have been instructed to disclose any limitations of data and unlabeled or investigational uses of products during their presentations.

Disclosure Statement

The following planners, speakers, and content reviewers, on behalf of themselves, have reported the following relevant financial relationships with any entity producing, marketing, reselling, or distributing health care goods or services consumed by, or used on patients: